Debra
I also have very large hands, but - trust me - you will do better with a fine needle. I still can't sew with a quilting between needle (the real short ones) and the straw needles (very long and thin) bend way too fast and don't give enough control. Try a size 10 sharp to begin with. It's fine enough not to fight you when you stitch and long enough to accomodate our larger fingers. I now sew with a size 12 sharp most of the time - depends on the thread I'm using. Leave the crow bars for heavy basting and sewing joints on teddies.