Funny you should mention that. I've got arthritis in my hands and just started using Elmer's school glue to hold seams. The school glue is water soluable. In fact, I just finished a quilt using Sharon Shamber's gluing method for the binding and have the best binding I've ever done. (The video for how to do this is on her web site.)
Sharon sufferes form hand tremors and has (out of necessity) devised some ingenious ways to quilt and sew; she just won won The Best Longarm award at AQS in Paducah this year so I guess she's something of an expert desipte the problem.
Needless to say I'm binding my quilts this way from now on. No pins and no pain! She has some books and videos out for many other techniques (such as her method for applique) and I think I'll ask for some of those for my Birthday!
-Irene